Browsing Research Articles by Issue Date
Now showing items 1-19 of 19
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Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans
(Vaccine, 2007)A phase I randomized, double blind, placebo-controlled trial to assess the immunogenicity of a multiclade HIV-1 DNA plasmid vaccine was conducted in 31 HIV-1-negative Ugandans. Following immunization with DNA at 0, 1, ... -
Factors associated with DPT 1-3 vaccine dropout in Kabarole district
(International Journal of Infectious Diseases, 2010)Background: Among the top ten causes of poor health in the district are complications due to vaccine preventable diseases notably diphtheria, pertussis and tetanus (DPT). In 2008, the DPT dropout rate in Kabarole was ... -
Assessing factors associated with CD4 cell absolute count in patients at Gulu Regional Referral Hospital: A case study by Marc Sam Opollo, Uganda
(South American Journal of Public Health, 2014)Background: This study is set to assess individual, environmental and medication factors associated with CD4 cell count in patients attending HIV/AIDS treatment and care clinic in Gulu Regional Referral Hospital. Gulu ... -
HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels
(The Journal of infectious diseases, 2015)Background. Untreated human immunodeficiency virus type 1 (HIV) infection is associated with persistent im mune activation, which is an independent driver of disease progression in European and United States cohorts. ... -
The Potential of Citizen- Driven Monitoring of Freshwater Snails in Schistosomiasis Research
(Citizen Science: Theory and Practice, 2021)Schistosomiasis is a tropical parasitic disease affecting more than 200 million people worldwide, predominantly in Africa. The World Health Organization recently highlighted the importance of targeted control of the ... -
Infection Prevention and Control at Lira University Hospital, Uganda: More Needs to Be Done
(Tropical Medicine and Infectious Disease, 2021)Globally, 5–15% of hospitalized patients acquire infections (often caused by antimicrobialresistant microbes) due to inadequate infection prevention and control (IPC) measures. We used the World Health Organization’s ... -
Knowledge, attitudes, and practices regarding schistosomiasis infection and prevention: A mixed-methods study among endemic communities of western Uganda
(PLOS NEGLECTED TROPICAL DISEASES, 2022)Schistosomiasis is one of the leading neglected tropical diseases, second to malaria in prevalence. In Uganda, more than 10 million people (25.6%) are currently infected, with prevalence in some areas as high as 90%, and ... -
Cholera epidemic amidst the COVID-19 pandemic in Moroto district, Uganda: Hurdles and opportunities for control
(PLOS Glob Public Health, 2022)Introduction On 21st March 2020, the first COVID-19 case was detected in Uganda and a COVID-19 pan demic declared. On the same date, a nationwide lockdown was instituted in response to the pandemic. Subsequently, more ... -
Health-seeking behaviour regarding schistosomiasis treatment in the absence of a mass drug administration (MDA) program: the case of endemic communities along Lake Albert in Western Uganda
(BMC Public Health, 2023)Introduction Schistosomiasis poses a serious public health problem and a social challenge affecting over 240 million people, the majority of whom live in sub-Saharan Africa. The World Health Organization (WHO) recommends ... -
A systematic review and meta-analysis of the prevalence of depression among breast cancer patients in Sub-Saharan Africa
(Avicenna Journal of Neuro Psycho Physiology, 2023)Background: Breast cancer is linked to neuropsychiatric conditions, particularly depression, which lowers life expectancy. Studies from Sub-Saharan Africa, however, have revealed conflicting prevalence rates of ... -
Maternal mental health screening and management by health workers in southwestern Uganda: a qualitative analysis of knowledge, practices, and challenges
(BMC Pregnancy and Childbirth, 2023)Background Maternal mental health (MMH) problems, such as perinatal depression, maternal anxiety, suicide ideation and puerperal psychosis among others, have a significant impact on maternal morbidity and mortality, as ... -
Parents’ Readiness to Vaccinate Their Children Aged 5 to 17 Years Against Covid-19 and Its Associated Factors in Lira District, Uganda
(Pediatric Health, Medicine and Therapeutics, 2023)Background: Data on parents’ readiness to vaccinate their children aged 5 to 17 years against COVID-19 is still scarce. This study assessed parents’ readiness to vaccinate their children aged 5 to 17 years against COVID-19 ... -
Factors associated with first antenatal care (ANC) attendance within 12 weeks of pregnancy among women in Lira City, Northern Uganda: a facility-based cross- sectional study
(BMJ, 2023)Objective This study aimed at assessing factors associated with first antenatal care (ANC) attendance within 12 weeks of pregnancy among women in Lira City. Design A cross-sectional study. Settings The study was ... -
Maternal mental health screening and management by health workers in southwestern Uganda: a qualitative analysis of knowledge, practices, and challenges
(BMC Pregnancy and Childbirth, 2023)Background Maternal mental health (MMH) problems, such as perinatal depression, maternal anxiety, suicide ideation and puerperal psychosis among others, have a significant impact on maternal morbidity and mortality, as ... -
Prevalence of dementia and its association with central nervous system infections among older persons in northern Uganda: cross-sectional community-based study
(BMC Geriatrics, 2023)Background Dementia is a condition in which there is deterioration in cognitive function beyond what might be expected from the usual consequence of biological aging. Few studies have been conducted on the prevalence ... -
Utilization of antiretroviral therapy services and associated factors among adolescents living with HIV in northern Uganda: A crosssectional study
(PLoS ONE, 2023)Background Suboptimal utilization of antiretroviral therapy (ART) services remains a problem among adolescents in low- and middle-income countries, which has a negative impact on their response to treatment and increases ... -
Access to family planning services and associated factors among young people in Lira city northern Uganda
(BMC Public Health, 2024)Background Access to family planning services among young people is crucial for reproductive health. This study explores the access and associated factors among young people in Lira City, Northern Uganda. Methods and ... -
The mediating role of self-control on the relations between adverse childhood experiences and substance use among adolescents in Uganda
(Frontiers in Psychology, 2024)Objective: Adverse childhood experiences (ACEs) are established risk factors for undesirable consequences in adolescence and early adulthood, including substance use and a lack of self-control. Based on the Social Bonds ... -
Empowering communities through citizen science and participatory action research: implementation of a schistosomiasis communication campaign in Uganda
(Humanities and Social Sciences Communications, 2024)Schistosomiasis is a water-related disease strongly linked with high-risk water and sanitation practices perpetuating disease transmission. In Uganda, despite health education and sensitisation efforts through communication ...
