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Now showing items 31-40 of 41
CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population
(Future Medicine Ltd: Pharmacogenomics, 2016)
To assess genotype effect on efavirenz (EFV) pharmacokinetics, treatment
outcomes and provide genotype-based EFV doses recommendations during for
tuberculosis (TB)-HIV-1 cotreatment. Materials & methods: EFV concentrations
from ...
Effect of the total crude extracts of Hibiscus sabdariffa on the immune system in the Wistar albino rats
(African Journal of Pharmacy and Pharmacology, 2013)
Medicinal herbs are commonly used worldwide as immune boosters and immunomodulators in the
management of various disease conditions. Many of these herbs commonly used have not been
scientifically evaluated for their ...
Effect of chronic alcohol consumption on the red blood cell count and RBC indices in the HIV infected patients on d4T/3TC/NVP drug regimen in Uganda
(International Journal of Basic & Clinical Pharmacology, 2013)
Alcohol consumption is common problem in Uganda. Among the types of alcohols consumed include beers, spirits, liqueurs, wines and traditional brew. These alcohols are easily accessible and consumed by many people including ...
Antimalarial Activity of Aspilia pruliseta, a Medicinal Plant from Uganda
(Planta Medica : Journal of Medicinal Plant and Natural Product Research, 2010)
Aspilia prulisetaSchweinf. (Asteraceae) is a medicinal plant in-digenous to Uganda and the neighboring countries of East Africa.It has been used extensively by the rural population for the treat-ment of fevers and malaria. ...
Field-adapted sampling of whole blood to determine the levels of amodiaquine and its metabolite in children with uncomplicated malaria treated with amodiaquine plus artesunate combination
(Malaria Journal, 2009)
Background: Artemisinin combination therapy (ACT) has been widely adopted as first-line
treatment for uncomplicated falciparum malaria. In Uganda, amodiaquine plus artesunate (AQ+AS),
is the alternative first-line regimen ...
Existing capacity to manage pharmaceuticals and related commodities in East Africa
(BioMed Central : Human Resources for Health, 2009)
Background: East African countries have in the recent past experienced a tremendous increase in the volume of
antiretroviral drugs. Capacity to manage these medicines in the region remains limited. Makerere University, ...
Incomplete reversal of genotypic resistance of Plasmodium falciparum to chloroquine after a decade of change in malaria treatment policy in Uganda
(Reports in Parasitology, 2016)
Background: The potential re-emergence of Plasmodium falciparum parasites sensitive to chloroquine provides an opportunity for the reintroduction of the drug in patient care. With the recent discovery and spread of artemisinin ...
Availability and utilization of the WHO recommended priority lifesaving medicines for under five-year old children in public health facilities in Uganda: a cross-sectional survey
(Journal of Pharmaceutical Policy and Practice, 2015)
Objectives: To explore the availability and utilization of the World Health Organization (WHO) recommended
priority life-saving medicines for children under five in public health facilities in Uganda.
Methods: We conducted ...
Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities
(Journal of Medicinal Plants Research, 2010)
Moringa oleifera grown and used in many countries around the world is a multi-purpose tree with medicinal, nutritional and socio-economic values. In Senegal and Benin, M. oleifera leaves are dispensed as powder at health ...
Acute toxicity effects of the methanolic extract of Fagara zanthoxyloides (Lam.) root-bark
(African Health Sciences, 2003)
Background: Fagara zanthoxyloides is a well known medicinal plant in Uganda. It is used extensively in malaria and other
infections. However nothing is known about its toxicity.
Objective: The objective of the study was ...