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Antimicrobial activity and phytochemical fingerprints of five crude extracts obtained from indigenous medicinal plants of Uganda
(Research in Pharmaceutical Biotechnology, 2017)
Five crude extracts from four Ugandan plants were screened in vitro for their antimicrobial activity and
phytochemical composition. They included the chloroform extracts of Bothliocline longipes, Maesa
lanceolata, Trimeria ...
Chronic alcohol use affects therapeutic steady state plasma drug concentrations of stavudine, lamivudine and nevirapine in HIV-infected patients during 9 months follow up period: WHO AUDIT tool application
(International Journal of Basic & Clinical Pharmacology, 2013)
Chronic alcohol consumption is a common problem among the HIV-infected patients on HAART. The study determined the effect of chronic alcohol use on steady state plasma drug concentrations of stavudine (d4T), lamivudine ...
The “child size medicines” concept: policy provisions in Uganda
(Journal of Pharmaceutical Policy and Practice, 2015)
Background: In 2007, the World Health Organization (WHO) launched the ‘make medicines child size’ (MMCS)
campaign by urging countries to prioritize procurement of medicines with appropriate strengths for children’s age
and ...
Patterns and Predictors of Self-Medication in Northern Uganda
(PLOS ONE, 2014)
Self-medication with antimicrobial agents is a common form of self-care among patients globally with the prevalence and
nature differing from country to country. Here we assessed the prevalence and predictors of antimicrobial ...
Antifungal Medicinal Plants Used by Communities Adjacent to Bwindi Impenetrable National Park, South-Western Uganda
(European Journal of Medicinal Plants, 2015)
Communities adjacent to Bwindi Impenetrable National Park (BINP) in South-western Uganda
largely depend on traditional herbal treatment for basic health care. The aim of this study was to
investigate the use of medicinal ...
Anti-Plasmodium falciparum activity of Aloe dawei and Justicia betonica
(African Journal of Pharmacy and Pharmacology, 2013)
Malaria is a fatal disease caused by different Plasmodium species of parasites and has remained the
major killer of humans worldwide especially the children under five years of age and pregnant women.
In this study, the ...
Phytochemicals and acute toxicity of Moringa oleifera roots in mice
(Journal of Pharmacognosy and Phytotherapy, 2011)
The phytochemicals used by plants to protect themselves against predators in Moringa oleifera roots were
qualitatively identified in the aqueous and ethanol extracts. Its acute toxicity in 24 h was evaluated in Swiss
albino ...
Community effectiveness of malaria treatment in Uganda---a long way to Abuja targets
(Annals of tropical paediatrics : Taylor & Francis, 2013)
ntroduction: At the Roll Back Malaria summit for African countries in Abuja, the heads of state committed to ensure that by the year 2005 at least 60% of those suffering from malaria would have access to effective treatment ...
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study
(BMC Infectious Diseases, 2013)
Background: HIV infection, anti-tuberculosis and efavirenz therapy are associated with neuropsychological effects.
We evaluated the influence of rifampicin cotreatment, efavirenz pharmacokinetics and pharmacogenetics ...
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
(British Journal of Clinical Pharmacology, 2009)
AIMS
Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim
was to develop an integrated population pharmacokinetic/pharmacogenetic model and
investigate the impact of genetic variations, ...