Faculty of Medicine: Recent submissions
Now showing items 41-60 of 204
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Prophylactic antibiotics to reduce pelvic infection in women having miscarriage surgery – The AIMS (Antibiotics in Miscarriage Surgery) trial: study protocol for a randomized controlled trial
(Trials, 2018)Abstract Background: The estimated annual global burden of miscarriage is 33 million out of 210 million pregnancies. Many women undergoing miscarriage have surgery to remove pregnancy tissues, resulting in miscarriage ... -
Spontaneous rupture of bladder in puerperium
(African Health Sciences, 2004)Abstract Spontaneous rupture of bladder and extravasation of urine in the peritoneum without evidence of trauma is rare. This condition is an emergency. It presents in a unique way therefore, the diagnosis and treatment ... -
A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery
(The New England Journal of Medicine, 2019)BACKGROUND Surgical intervention is needed in some cases of spontaneous abortion to remove retained products of conception. Antibiotic prophylaxis may reduce the risk of pelvic infection, which is an important complication ... -
Obstetric Referrals to a Tertiary Hospital in Northern Uganda - A One Year Experience
(Jemds.com, 2020)BACKGROUND Delay in referral adversely affects maternal and neonatal outcome. We wanted to review the obstetric referrals, source of referrals, appropriateness of referrals and document the maternal and perinatal outcomes ... -
The Effectiveness of Post-Operative Pain Regime in C-Section Mothers, Lira Regional Referral Hospita
(IAR J. Med Ser, 2023)Purpose: This study sought to explore the effectiveness of pain management in post-caesarian section mothers in Lira Regional Referral hospital Methods: Using a descriptive cross sectional design, data was collected from ... -
Anti-malarial drug use, appropriateness and associated factors among children under-fve with febrile illnesses presenting to a tertiary health facility: a cross sectional study
(Malaria Journal, 2023)Background Malaria is endemic in 95% of Uganda and constitutes the country’s most signifcant public health prob lem—being the leading cause of morbidity and mortality, especially among children under fve years of age. The ... -
Predictors of Unintended Pregnancy Among Adolescent Girls During the Second Wave of COVID-19 Pandemic in Oyam District in Northern Uganda
(Open Access Journal of Contraception, 2023)Background: In Uganda, unintended pregnancies are responsible for one in three births with detrimental consequences, a situation that worsened during COVID-19. Thus, the present examined unplanned pregnancy and its ... -
Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle
(Proceedings of the Nutrition Society, 2004)Contractile activity induces mitochondrial biogenesis and increases glucose transport capacity in muscle. There has been much research on the mechanisms responsible for these adaptations. The present paper reviews the ... -
Uric acid and transforming growth factor in fructose-induced production of reactive oxygen species in skeletal muscle
(Oxford University Press, 2016)The consumption of fructose, a major constituent of the modern diet, has raised increasing concern about the effects of fructose on health. Research suggests that excessive intake of fructose (>50 g/d) causes hyperuricemia, ... -
Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro
(J. Appl. Physiol., 2000)Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro. J. Appl. Physiol. 88: 1072–1075, 2000.—Exercise acutely stimulates muscle glucose transport and also brings about ... -
CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene
(Am J Physiol Endocrinol Metab 295, 2007)CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene. Am J Physiol Endocrinol Metab 295: E698 –E704, 2008. First published July 22, 2008; ... -
Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca2+
(Am J Physiol Endocrinol Metab 282, 2002)Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca2 . Am J Physiol Endocrinol Metab 282: E1008–E1013, 2002; 10.1152/ ajpendo.00512.2001.—There is evidence suggesting that adaptive increases ... -
Intermittent increases in cytosolic Ca2 stimulate mitochondrial biogenesis in muscle cells
(Am J Physiol Endocrinol Metab 283, 2002)Intermittent increases in cytosolic Ca2 stimulate mitochondrial biogenesis in muscle cells. Am J Physiol Endocrinol Metab 283: E1040–E1045, 2002. First published July 24, 2002; 10.1152/ajpendo.00242.2002.—Muscle contractions ... -
Exercise and CaMK activation both increase the binding of MEF2A to the Glut4 promoter in skeletal muscle in vivo
(Am J Physiol Endocrinol Metab 292, 2006)Exercise and CaMK activation both increase the binding of MEF2A to the Glut4 promoter in skeletal muscle in vivo. Am J Physiol Endocrinol Metab 292: E413–E420, 2007. First published September 19, 2006; doi:10.1152/ajp ... -
The role of CaMKII in regulating GLUT4 expression in skeletal muscle
(Am J Physiol Endocrinol Metab, 2012)The role of CaMKII in regulating GLUT4 expression in skeletal muscle. Am J Physiol Endocrinol Metab 303: E322–E331, 2012. First published April 10, 2012; doi:10.1152/ajpendo.00091.2012.—Contractile activity during ... -
Gaps in available published data on abortion in Uganda and the missed opportunity to inform policy and practice
(International Journal of Gynecology & Obstetrics., 2022)Globally, 25% of pregnancies end up in induced abortion, the majority of which are unsafe. Abortion is safe when conducted according to WHO recommendations. The objective of the present study was to identify gaps in the ... -
Landslide disasters in eastern Uganda: post‑traumatic stress disorder and its correlates among survivors in Bududa district
(BMC Psychology, 2022)Background: Post-traumatic stress disorder is the commonly reported psychiatric morbidity among the survivors of natural disasters. However, its prevalence particularly in Bududa, Eastern Uganda is largely unknown. Aims ... -
Predictors of Adherence to Routine Immunization Schedule Among Caretakers of Children Aged 10 to 18 Months in Lira City, Uganda
(Global Pediatric Health, 2022)Background. Although the majority of nations have routine immunization programs in place as a public health strategy, more than 1.5 million children under the age of 5 die yearly worldwide due to inadequate vaccination ... -
Oral–visceral iatrogenic Kaposi sarcoma following treatment for acute lymphoblastic leukemia: a case report and review of the literature
(Journal of Medical Case Reports, 2022)Background: There have hardly been any reported cases of children presenting with Kaposi sarcoma as a second malignancy following treatment for acute lymphoblastic leukemia outside a transplant setting. Case presentation: ... -
The clinicopathological profile and value of multidisciplinary management of pediatric brain tumors in a low-income setting
(Taylor & Francis, 2022-10-31)ABSTRACT Brain tumors are the most common solid tumors in children and a leading cause of cancer-related mortality in children worldwide. Data on the epidemiology and management of pediatric brain tumors in Uganda are ...
