Faculty of Medicine: Recent submissions
Now showing items 41-60 of 197
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Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle
(Proceedings of the Nutrition Society, 2004)Contractile activity induces mitochondrial biogenesis and increases glucose transport capacity in muscle. There has been much research on the mechanisms responsible for these adaptations. The present paper reviews the ... -
Uric acid and transforming growth factor in fructose-induced production of reactive oxygen species in skeletal muscle
(Oxford University Press, 2016)The consumption of fructose, a major constituent of the modern diet, has raised increasing concern about the effects of fructose on health. Research suggests that excessive intake of fructose (>50 g/d) causes hyperuricemia, ... -
Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro
(J. Appl. Physiol., 2000)Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro. J. Appl. Physiol. 88: 1072–1075, 2000.—Exercise acutely stimulates muscle glucose transport and also brings about ... -
CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene
(Am J Physiol Endocrinol Metab 295, 2007)CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene. Am J Physiol Endocrinol Metab 295: E698 –E704, 2008. First published July 22, 2008; ... -
Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca2+
(Am J Physiol Endocrinol Metab 282, 2002)Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca2 . Am J Physiol Endocrinol Metab 282: E1008–E1013, 2002; 10.1152/ ajpendo.00512.2001.—There is evidence suggesting that adaptive increases ... -
Intermittent increases in cytosolic Ca2 stimulate mitochondrial biogenesis in muscle cells
(Am J Physiol Endocrinol Metab 283, 2002)Intermittent increases in cytosolic Ca2 stimulate mitochondrial biogenesis in muscle cells. Am J Physiol Endocrinol Metab 283: E1040–E1045, 2002. First published July 24, 2002; 10.1152/ajpendo.00242.2002.—Muscle contractions ... -
Exercise and CaMK activation both increase the binding of MEF2A to the Glut4 promoter in skeletal muscle in vivo
(Am J Physiol Endocrinol Metab 292, 2006)Exercise and CaMK activation both increase the binding of MEF2A to the Glut4 promoter in skeletal muscle in vivo. Am J Physiol Endocrinol Metab 292: E413–E420, 2007. First published September 19, 2006; doi:10.1152/ajp ... -
The role of CaMKII in regulating GLUT4 expression in skeletal muscle
(Am J Physiol Endocrinol Metab, 2012)The role of CaMKII in regulating GLUT4 expression in skeletal muscle. Am J Physiol Endocrinol Metab 303: E322–E331, 2012. First published April 10, 2012; doi:10.1152/ajpendo.00091.2012.—Contractile activity during ... -
Gaps in available published data on abortion in Uganda and the missed opportunity to inform policy and practice
(International Journal of Gynecology & Obstetrics., 2022)Globally, 25% of pregnancies end up in induced abortion, the majority of which are unsafe. Abortion is safe when conducted according to WHO recommendations. The objective of the present study was to identify gaps in the ... -
Landslide disasters in eastern Uganda: post‑traumatic stress disorder and its correlates among survivors in Bududa district
(BMC Psychology, 2022)Background: Post-traumatic stress disorder is the commonly reported psychiatric morbidity among the survivors of natural disasters. However, its prevalence particularly in Bududa, Eastern Uganda is largely unknown. Aims ... -
Predictors of Adherence to Routine Immunization Schedule Among Caretakers of Children Aged 10 to 18 Months in Lira City, Uganda
(Global Pediatric Health, 2022)Background. Although the majority of nations have routine immunization programs in place as a public health strategy, more than 1.5 million children under the age of 5 die yearly worldwide due to inadequate vaccination ... -
Oral–visceral iatrogenic Kaposi sarcoma following treatment for acute lymphoblastic leukemia: a case report and review of the literature
(Journal of Medical Case Reports, 2022)Background: There have hardly been any reported cases of children presenting with Kaposi sarcoma as a second malignancy following treatment for acute lymphoblastic leukemia outside a transplant setting. Case presentation: ... -
The clinicopathological profile and value of multidisciplinary management of pediatric brain tumors in a low-income setting
(Taylor & Francis, 2022-10-31)ABSTRACT Brain tumors are the most common solid tumors in children and a leading cause of cancer-related mortality in children worldwide. Data on the epidemiology and management of pediatric brain tumors in Uganda are ... -
Traditional herbal remedies for managing COVID-19 major symptoms: A case study of Kole district, Northern Uganda
(TMR Pharmacology Research, 2021)Background: Today, the world is battling COVID-19 which has claimed millions of lives within a short period. As biotechnological research is in progress, it’s expedient to explore alternative sources of medication. Exploring ... -
Breast‑feeding practices and maternal employment in health facilities of Lira District, Northern Uganda
(Bulletin of the National Research Centre, 2022)Background: In Uganda, many working mothers stop breast-feeding before the end of the mandatory maternity leave of 60 days. Inadequate breast-feeding is a risk factor for infant morbidity and mortality. Thus, understanding ... -
Major Limb Loss and Prosthesis Use in the Post Conflict era in Acholi Sub-Region, Northern Uganda
(International Journal of Science Academic Research, 2022)Introduction: This study assessed amputees’ residual limb stump in the post war era of Acholi sub-region for suitability of prosthetic fit use and associated challenges with their current prosthesis and psycho-socio ... -
HIV/AIDS Stigma Reduction as a Risk Factor for New HIV Infections: A Lived Experience Study of HIV Positive Young Women in a Rural Setting
(2022-06-05)Background: HIV/AIDS-related stigma is a global problem among HIV patients with far-reaching implications. However, there is an increase in HIV infections, especially among young women. Objective: This study aimed at ... -
The Effect of Reward Practices and Health Service Delivery in Health Facilities—Kwania District Uganda
(Journal of Human Resource and Sustainability Studies, 2022)Purpose: This study aimed to examine the relationship and effect of intrinsic and extrinsic reward practices on health service delivery. Methods: Data was collected prospectively from Thirteen Government health facilities ... -
Knowledge, Practice of Health Workers and Surgical Site Infections at Lira Regional Referral Hospital (LRRH) And Lira University Teaching Hospital (LUTH)
(International Journal of Science Academic Research, 2022)Purpose: The effect of knowledge and practice of health workers (HWs) on surgical site infection (SSI) has never been documented in our area and such knowledge gaps has made advocating for allocation of resources to tackle ... -
Pre‑hospital exposures to antibiotics among children presenting with fever in northern Uganda: a facility‑based cross‑sectional study
(BMC Pediatrics, 2022)Abstract Background: The rise in the indiscriminate use of antibiotics has become a major global public health problem and presents the biggest global health challenge in the twenty-first century. In developing countries, ...