Faculty of Medicine: Recent submissions
Now showing items 21-40 of 191
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Plasma levels of DDE/DDT and liver function in malaria control personnel 6 months after indoor residual spraying with DDT in northern Uganda, 2008
(South African Medical Journal, 2008)Objective. We investigated the relationship between plasma levels of dichlorodiphenyltrichloroethane (DDT) and liver function in malaria control personnel 6 months after one round of DDT indoor residual spraying ... -
Neuroinflammation and Not Tauopathy Is a Predominant Pathological Signature of Nodding Syndrome
(Journal of Neuropathology & Experimental Neurology, 2019)Nodding syndrome (NS) is an epileptic disorder occurring in chil dren in African onchocerciasis endemic regions. Here, we describe the pathological changes in 9 individuals from northern Uganda who died with NS (n ¼ 5) ... -
Neuropathological Changes in Nakalanga Syndrome—A Case Report
(Pathogens, 2021)Nakalanga syndrome is a clinical manifestation of onchocerciasis-associated epilepsy characterized by stunting, delayed or absent secondary sexual development and skeletal deformities, and is often accompanied by epileptic ... -
Chronic stress and its correlates among nurses: A case of Central Uganda
(Avicenna J Neuro Psycho Physiology, 2023)Background: Despite an overwhelming disease burden, nursing shortages are evident in Sub-Saharan Africa, with the potential for significant healthcare crises. Nurses face increased work demands and chronic stress due to a ... -
Chronic stress and coping mechanisms among nurses in Lango sub-region, northern Uganda
(Wiley Nursing Open, 2023)Aim: This study aimed to assess chronic stress and coping mechanisms among nurses in Lango sub-region, northern Uganda, conducted between May and June 2022. Design: Institutional-based cross-sectional design conducted ... -
Phenomenology of Induced Abortion in Northern Uganda Among HIV-Positive Women Following an Unintended Pregnancy
(Open Access Journal of Contraception, 2023)Background: More than half of pregnancies in Uganda are unintended, and nearly a third of these end in abortion. However, little research has focused on women living with HIV’s subjective experiences following induced ... -
Etiological Factors of Neonatal Mortality in a Large Rural Hospital- St. Mary’s Hospital Lacor
(Scientific Research Journal of Medical Sciences, 2023)Purpose: The aim of the study was to identify the gaps for further improvement of neonatal survival at St. Mary’s Hospital Lacor, Gulu city Uganda. Objective: To determine the etiological factors associated with neonatal ... -
Prophylactic antibiotics to reduce pelvic infection in women having miscarriage surgery – The AIMS (Antibiotics in Miscarriage Surgery) trial: study protocol for a randomized controlled trial
(Trials, 2018)Abstract Background: The estimated annual global burden of miscarriage is 33 million out of 210 million pregnancies. Many women undergoing miscarriage have surgery to remove pregnancy tissues, resulting in miscarriage ... -
Spontaneous rupture of bladder in puerperium
(African Health Sciences, 2004)Abstract Spontaneous rupture of bladder and extravasation of urine in the peritoneum without evidence of trauma is rare. This condition is an emergency. It presents in a unique way therefore, the diagnosis and treatment ... -
A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery
(The New England Journal of Medicine, 2019)BACKGROUND Surgical intervention is needed in some cases of spontaneous abortion to remove retained products of conception. Antibiotic prophylaxis may reduce the risk of pelvic infection, which is an important complication ... -
Obstetric Referrals to a Tertiary Hospital in Northern Uganda - A One Year Experience
(Jemds.com, 2020)BACKGROUND Delay in referral adversely affects maternal and neonatal outcome. We wanted to review the obstetric referrals, source of referrals, appropriateness of referrals and document the maternal and perinatal outcomes ... -
The Effectiveness of Post-Operative Pain Regime in C-Section Mothers, Lira Regional Referral Hospita
(IAR J. Med Ser, 2023)Purpose: This study sought to explore the effectiveness of pain management in post-caesarian section mothers in Lira Regional Referral hospital Methods: Using a descriptive cross sectional design, data was collected from ... -
Anti-malarial drug use, appropriateness and associated factors among children under-fve with febrile illnesses presenting to a tertiary health facility: a cross sectional study
(Malaria Journal, 2023)Background Malaria is endemic in 95% of Uganda and constitutes the country’s most signifcant public health prob lem—being the leading cause of morbidity and mortality, especially among children under fve years of age. The ... -
Predictors of Unintended Pregnancy Among Adolescent Girls During the Second Wave of COVID-19 Pandemic in Oyam District in Northern Uganda
(Open Access Journal of Contraception, 2023)Background: In Uganda, unintended pregnancies are responsible for one in three births with detrimental consequences, a situation that worsened during COVID-19. Thus, the present examined unplanned pregnancy and its ... -
Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle
(Proceedings of the Nutrition Society, 2004)Contractile activity induces mitochondrial biogenesis and increases glucose transport capacity in muscle. There has been much research on the mechanisms responsible for these adaptations. The present paper reviews the ... -
Uric acid and transforming growth factor in fructose-induced production of reactive oxygen species in skeletal muscle
(Oxford University Press, 2016)The consumption of fructose, a major constituent of the modern diet, has raised increasing concern about the effects of fructose on health. Research suggests that excessive intake of fructose (>50 g/d) causes hyperuricemia, ... -
Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro
(J. Appl. Physiol., 2000)Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro. J. Appl. Physiol. 88: 1072–1075, 2000.—Exercise acutely stimulates muscle glucose transport and also brings about ... -
CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene
(Am J Physiol Endocrinol Metab 295, 2007)CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene. Am J Physiol Endocrinol Metab 295: E698 –E704, 2008. First published July 22, 2008; ... -
Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca2+
(Am J Physiol Endocrinol Metab 282, 2002)Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca2 . Am J Physiol Endocrinol Metab 282: E1008–E1013, 2002; 10.1152/ ajpendo.00512.2001.—There is evidence suggesting that adaptive increases ... -
Intermittent increases in cytosolic Ca2 stimulate mitochondrial biogenesis in muscle cells
(Am J Physiol Endocrinol Metab 283, 2002)Intermittent increases in cytosolic Ca2 stimulate mitochondrial biogenesis in muscle cells. Am J Physiol Endocrinol Metab 283: E1040–E1045, 2002. First published July 24, 2002; 10.1152/ajpendo.00242.2002.—Muscle contractions ...