Faculty of Medicine: Recent submissions
Now showing items 21-40 of 204
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A Systematic Review and Meta-analysis of the Prevalence of Depression among Breast Cancer Patients in Sub-Saharan Africa
(Avicenna Journal of Neuropsychophysiology, 2023)Background: Breast cancer is linked to neuropsychiatric conditions, particularly depression, which lowers life expectancy. Studies from Sub-Saharan Africa, however, have revealed conflicting prevalence rates of ... -
Delays in Cryptococcal Meningitis Diagnosis and Care: A Mixed Methods Study in Rural Uganda
(Annals of global health,, 2022)Background: Cryptococcal meningitis (CM) remains a major cause of mortality for HIV infected persons in sub-Saharan Africa, despite widespread access to antiretroviral therapy. Delays in CM diagnosis and treatment ... -
Prevalence of Intestinal Helminth Coinfection in Drug-Resistant Tuberculosis in Uganda
(Oxford University Press., 2022)Background. Although a third of people with tuberculosis (TB) are estimated to be coinfected with helminths, the prevalence is largely unknown among people with drug-resistant TB (DR-TB). We determined the prevalence of ... -
Blood Culture Testing Outcomes among Non-Malarial Febrile Children at Antimicrobial Resistance Surveillance Sites in Uganda, 2017–2018
(Tropical Medicine and Infectious Disease, 2021): Blood culture (BC) processes are critical to the utility of diagnostic testing, bloodstream infection (BSI) management, and antimicrobial resistance (AMR) surveillance. While Uganda has established BC guidelines, often ... -
High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy–Experienced Human Immunodeficiency Virus–Infected Patients in Northern Uganda in the Era of “Test and Treat”: Implications for Cryptococcal Screening Programs
(Open forum infectious diseases, 2022)Background. The impact of the “test and treat” program for human immunodeficiency virus (HIV) treatment in rural areas of Uganda on cryptococcal antigen (CrAg) screening or cryptococcal meningitis (CM) is poorly ... -
Challenges associated with the roll-out of HCC surveillance in sub-Saharan Africa - the case of Uganda
(Journal of Hepatology, 2020)In sub-Saharan Africa, where HBV infections are the main cause of HCC, surveillance programs are mostly not available.2 Nonetheless, with an incidence rate of 8.9 cases per 100,000 inhabitants per year, which is likely ... -
Lack of education, knowledge, and supplies are barriers to cryptococcal meningitis care among nurses and other healthcare providers in rural Uganda: A mixed methods study
(Nurse Education Today, 2023)Abstract Background Cryptococcal meningitis (CM) is one of the deadliest opportunistic infections related to HIV/AIDS. A research gap exists surrounding the barriers to CM diagnosis, treatment delivery, and care from ... -
Utilization of antiretroviral therapy services and associated factors among adolescents living with HIV in northern Uganda: A cross-sectional study
(PLoS ONE, 2023)Background Suboptimal utilization of antiretroviral therapy (ART) services remains a problem among adolescents in low- and middle-income countries, which has a negative impact on their response to treatment and increases ... -
Impact of a Cryptococcal meningitis diagnosis and treatment program at Lira Regional Referral Hospital in rural, Northern Uganda
(PLOS global public health, 2022)Abstract In rural areas of sub-Saharan Africa, infrastructure and resources for treatment of crypto coccal meningitis (CM) are often lacking. We introduced a CM diagnosis and treatment pro gram (CM-DTP) at Lira Regional ... -
Knowledge and compliance with Covid-19 infection prevention and control measures among health workers in regional referral hospitals in northern Uganda: a cross sectional online survey [version 2; peer review: 1 approved, 1 approved with reservations]
(F1000Research, 2021)Background: Infection prevention and control (IPC) has increasingly been underscored as a key tool for limiting the transmission of coronavirus disease 2019 (Covid-19) and safeguarding health workers from infections ... -
Improving the accuracy of heart failure diagnosis in low-resource settings through task sharing and decentralization
(Global Health Action, 2019)Background: Task sharing of TTE may improve capacity for heart failure diagnosis and management in patients in remote, low-resource settings but the impact on diagnostic accuracy and patient outcomes has not been ... -
Nodding syndrome in Uganda is a tauopathy
(Acta neuropathologica, 2018)Nodding syndrome is an epidemic neurologic disorder of unknown cause that affects children in the subsistence-farming communities of East Africa. We report the neuropathologic findings in five fatal cases (13–18 years of ... -
The spectrum of disease and tau pathology of nodding syndrome in Uganda
(Brain, 2021)Nodding syndrome is an enigmatic recurrent epidemic neurologic disease that affects children in East Africa. The illness begins with vertical nodding of the head and can progress to grand mal seizures and death after ... -
Plasma levels of DDE/DDT and liver function in malaria control personnel 6 months after indoor residual spraying with DDT in northern Uganda, 2008
(South African Medical Journal, 2008)Objective. We investigated the relationship between plasma levels of dichlorodiphenyltrichloroethane (DDT) and liver function in malaria control personnel 6 months after one round of DDT indoor residual spraying ... -
Neuroinflammation and Not Tauopathy Is a Predominant Pathological Signature of Nodding Syndrome
(Journal of Neuropathology & Experimental Neurology, 2019)Nodding syndrome (NS) is an epileptic disorder occurring in chil dren in African onchocerciasis endemic regions. Here, we describe the pathological changes in 9 individuals from northern Uganda who died with NS (n ¼ 5) ... -
Neuropathological Changes in Nakalanga Syndrome—A Case Report
(Pathogens, 2021)Nakalanga syndrome is a clinical manifestation of onchocerciasis-associated epilepsy characterized by stunting, delayed or absent secondary sexual development and skeletal deformities, and is often accompanied by epileptic ... -
Chronic stress and its correlates among nurses: A case of Central Uganda
(Avicenna J Neuro Psycho Physiology, 2023)Background: Despite an overwhelming disease burden, nursing shortages are evident in Sub-Saharan Africa, with the potential for significant healthcare crises. Nurses face increased work demands and chronic stress due to a ... -
Chronic stress and coping mechanisms among nurses in Lango sub-region, northern Uganda
(Wiley Nursing Open, 2023)Aim: This study aimed to assess chronic stress and coping mechanisms among nurses in Lango sub-region, northern Uganda, conducted between May and June 2022. Design: Institutional-based cross-sectional design conducted ... -
Phenomenology of Induced Abortion in Northern Uganda Among HIV-Positive Women Following an Unintended Pregnancy
(Open Access Journal of Contraception, 2023)Background: More than half of pregnancies in Uganda are unintended, and nearly a third of these end in abortion. However, little research has focused on women living with HIV’s subjective experiences following induced ... -
Etiological Factors of Neonatal Mortality in a Large Rural Hospital- St. Mary’s Hospital Lacor
(Scientific Research Journal of Medical Sciences, 2023)Purpose: The aim of the study was to identify the gaps for further improvement of neonatal survival at St. Mary’s Hospital Lacor, Gulu city Uganda. Objective: To determine the etiological factors associated with neonatal ...
