Browsing Faculty of Public Health by Issue Date
Now showing items 1-20 of 97
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Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans
(Vaccine, 2007)A phase I randomized, double blind, placebo-controlled trial to assess the immunogenicity of a multiclade HIV-1 DNA plasmid vaccine was conducted in 31 HIV-1-negative Ugandans. Following immunization with DNA at 0, 1, ... -
Factors associated with DPT 1-3 vaccine dropout in Kabarole district
(International Journal of Infectious Diseases, 2010)Background: Among the top ten causes of poor health in the district are complications due to vaccine preventable diseases notably diphtheria, pertussis and tetanus (DPT). In 2008, the DPT dropout rate in Kabarole was ... -
Prevalence of HIV-AssociatedMetabolic Abnormalities among Patients Taking First-Line Antiretroviral Therapy in Uganda
(International Scholarly Research Network, 2012)Introduction. While the introduction of highly active antiretroviral therapy decreased HIV-related morbidity and mortality rates in the sub-Saharan Africa, a subsequent increase in metabolic abnormalities has been observed. ... -
Assessing factors associated with CD4 cell absolute count in patients at Gulu Regional Referral Hospital: A case study by Marc Sam Opollo, Uganda
(South American Journal of Public Health, 2014)Background: This study is set to assess individual, environmental and medication factors associated with CD4 cell count in patients attending HIV/AIDS treatment and care clinic in Gulu Regional Referral Hospital. Gulu ... -
A case of Shapiro’s Syndrome in an African young man
(Case Reports in Internal Medicine, 2015)Shapiro’s syndrome is a rare congenital neurological disease characterized by episodes of excessive sweating and hypothermia, and by complete/partial agenesis of the corpus callosum. We report an 18 year-old male who was ... -
HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels
(The Journal of infectious diseases, 2015)Background. Untreated human immunodeficiency virus type 1 (HIV) infection is associated with persistent im mune activation, which is an independent driver of disease progression in European and United States cohorts. ... -
Prevalence and determinants of metabolic syndrome: a cross-sectional survey of general medical outpatient clinics using National Cholesterol Education Program-Adult Treatment Panel III criteria in Botswana
(Dovepress, 2016)Background: Low- and middle-income countries, including Botswana, are facing rising prevalence of obesity and obesity-related cardiometabolic complications. Very little information is known about clustering of cardiovascular ... -
Validity of the Finnish Diabetes Risk Score for Detecting Undiagnosed Type 2 Diabetes among General Medical Outpatients in Botswana
(ournal of diabetes research, 2016)This was a cross-sectional study designed to assess the validity of the Finnish Diabetes Risk Score for detecting undiagnosed type 2 diabetes among general medical outpatients in Botswana. Participants aged ≥20 years ... -
Presentation and mortality of patients hospitalised with acute heart failure in Botswana
(Cardiovascular journal of Africa, 2017)Introduction: Heart failure is a common cause of hospitalisation and therefore contributes to in-hospital outcomes such as mortality. In this study we describe patient characteristics and outcomes of acute heart failure ... -
The utilization of HbA1c test in the screening and diagnosis of type 2 diabetes mellitus: An outpatient clinics survey in Botswana
(Journal of Diabetes and Endocrinology, 2017)This study aimed to assess HbA1c performance against single fasting blood glucose (FBG) for diagnosis of undiagnosed type 2 diabetes (T2D) and impaired fasting glycaemia (IFG) among general medical outpatients in Botswana. ... -
Undiagnosed and diagnosed diabetes mellitus among hospitalised acute heart failure patients in Botswana
(SAGE open medicine, 2017)Objective: The objective of this study was to determine the burden of diagnosed and undiagnosed type 2 diabetes mellitus among patients hospitalised with acute heart failure in Botswana. Methods: The study enrolled 193 ... -
Anaemia, renal dysfunction and in-hospital outcomes in patients with heart failure in Botswana
(South African Medical Journal, 2018)Background. Anaemia and renal dysfunction are associated with an increased morbidity and mortality in heart failure (HF) patients. Objective. To estimate the frequency and impact of anaemia and renal dysfunction on ... -
Coping with post-war mental health problems among survivors of violence in Northern Uganda: Findings from the WAYS study
(J Health Psychol, 2018-05-01)Cognitive emotion regulation strategies and mental health problems were assessed in a sample of war-affected youth in Northern Uganda. Univariable and multivariable regression models were fitted to assess the influence of ... -
Glycaemic, blood pressure and lowdensity lipoprotein-cholesterol control among patients with diabetes mellitus in a specialised clinic in Botswana: a cross-sectional study
(BMJ Open, 2019)Objective Control of glycaemic, hypertension and lowdensity lipoprotein-cholesterol (LDL-C) among patients with type 2 diabetes mellitus (T2DM) is vital for the prevention of cardiovascular diseases. The current study was ... -
Knowledge of alcohol-disease links and sociodemographic factors as predictors of support for alcohol-related policies among university students in Botswana
(Drugs: Education, Prevention and Policy, 2019)Background: Worldwide, harmful alcohol use is causally related to about 60 diseases and is linked to about 3.3 million deaths annually. Yet, awareness of alcohol-disease links is low. Objective: This study aims to assess ... -
Autoimmune skin disease among dermatology outpatients in Botswana: a retrospective review
(International journal of dermatology, 2019)Background There is a paucity of data describing autoimmune skin diseases in sub- Saharan Africa and in HIV positive cohorts. We describe the incidence of autoimmune skin diseases in public dermatology clinics in ... -
Stroke and HIV in Botswana: A prospective study of risk factors and outcomes
(Journal of the Neurological Sciences, 2020)Objective: HIV is associated with an increased risk of stroke, but there are sparse data on risk factors for stroke in people living with HIV in Sub-Saharan African. The goal of this study was to identify HIV-specific ... -
Predictors of Somatic Symptomatology in War-Affected Youth in Northern Uganda: Findings from the WAYS Study
(Psychological Studies, 2020)War experiences have been shown to have adverse long-term psychological sequelae. Nevertheless, the roles of different types of war events in predicting which mental health outcomes remain unclear. This study investigated ... -
Novel Education Modules Addressing the Underrepresentation of Skin of Color in Dermatology Training
(Journal of Cutaneous Medicine and Surgery, 2021)Background: Representative images of pathology in patients with skin of color are lacking in most medical education resources. This particularly affects training in dermatology, which relies heavily on the use of images ... -
The Potential of Citizen- Driven Monitoring of Freshwater Snails in Schistosomiasis Research
(Citizen Science: Theory and Practice, 2021)Schistosomiasis is a tropical parasitic disease affecting more than 200 million people worldwide, predominantly in Africa. The World Health Organization recently highlighted the importance of targeted control of the ...
