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Patterns and Predictors of Self-Medication in Northern Uganda
(PLOS ONE, 2014)
Self-medication with antimicrobial agents is a common form of self-care among patients globally with the prevalence and
nature differing from country to country. Here we assessed the prevalence and predictors of antimicrobial ...
Antifungal Medicinal Plants Used by Communities Adjacent to Bwindi Impenetrable National Park, South-Western Uganda
(European Journal of Medicinal Plants, 2015)
Communities adjacent to Bwindi Impenetrable National Park (BINP) in South-western Uganda
largely depend on traditional herbal treatment for basic health care. The aim of this study was to
investigate the use of medicinal ...
Anti-Plasmodium falciparum activity of Aloe dawei and Justicia betonica
(African Journal of Pharmacy and Pharmacology, 2013)
Malaria is a fatal disease caused by different Plasmodium species of parasites and has remained the
major killer of humans worldwide especially the children under five years of age and pregnant women.
In this study, the ...
Phytochemicals and acute toxicity of Moringa oleifera roots in mice
(Journal of Pharmacognosy and Phytotherapy, 2011)
The phytochemicals used by plants to protect themselves against predators in Moringa oleifera roots were
qualitatively identified in the aqueous and ethanol extracts. Its acute toxicity in 24 h was evaluated in Swiss
albino ...
Community effectiveness of malaria treatment in Uganda---a long way to Abuja targets
(Annals of tropical paediatrics : Taylor & Francis, 2013)
ntroduction: At the Roll Back Malaria summit for African countries in Abuja, the heads of state committed to ensure that by the year 2005 at least 60% of those suffering from malaria would have access to effective treatment ...
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study
(BMC Infectious Diseases, 2013)
Background: HIV infection, anti-tuberculosis and efavirenz therapy are associated with neuropsychological effects.
We evaluated the influence of rifampicin cotreatment, efavirenz pharmacokinetics and pharmacogenetics ...
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
(British Journal of Clinical Pharmacology, 2009)
AIMS
Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim
was to develop an integrated population pharmacokinetic/pharmacogenetic model and
investigate the impact of genetic variations, ...
CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population
(Future Medicine Ltd: Pharmacogenomics, 2016)
To assess genotype effect on efavirenz (EFV) pharmacokinetics, treatment
outcomes and provide genotype-based EFV doses recommendations during for
tuberculosis (TB)-HIV-1 cotreatment. Materials & methods: EFV concentrations
from ...
Effect of the total crude extracts of Hibiscus sabdariffa on the immune system in the Wistar albino rats
(African Journal of Pharmacy and Pharmacology, 2013)
Medicinal herbs are commonly used worldwide as immune boosters and immunomodulators in the
management of various disease conditions. Many of these herbs commonly used have not been
scientifically evaluated for their ...
Effect of chronic alcohol consumption on the red blood cell count and RBC indices in the HIV infected patients on d4T/3TC/NVP drug regimen in Uganda
(International Journal of Basic & Clinical Pharmacology, 2013)
Alcohol consumption is common problem in Uganda. Among the types of alcohols consumed include beers, spirits, liqueurs, wines and traditional brew. These alcohols are easily accessible and consumed by many people including ...