Lira University institutional Repository: Recent submissions
Now showing items 101-120 of 627
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High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy–Experienced Human Immunodeficiency Virus–Infected Patients in Northern Uganda in the Era of “Test and Treat”: Implications for Cryptococcal Screening Programs
(Open forum infectious diseases, 2022)Background. The impact of the “test and treat” program for human immunodeficiency virus (HIV) treatment in rural areas of Uganda on cryptococcal antigen (CrAg) screening or cryptococcal meningitis (CM) is poorly ... -
Challenges associated with the roll-out of HCC surveillance in sub-Saharan Africa - the case of Uganda
(Journal of Hepatology, 2020)In sub-Saharan Africa, where HBV infections are the main cause of HCC, surveillance programs are mostly not available.2 Nonetheless, with an incidence rate of 8.9 cases per 100,000 inhabitants per year, which is likely ... -
Lack of education, knowledge, and supplies are barriers to cryptococcal meningitis care among nurses and other healthcare providers in rural Uganda: A mixed methods study
(Nurse Education Today, 2023)Abstract Background Cryptococcal meningitis (CM) is one of the deadliest opportunistic infections related to HIV/AIDS. A research gap exists surrounding the barriers to CM diagnosis, treatment delivery, and care from ... -
Utilization of antiretroviral therapy services and associated factors among adolescents living with HIV in northern Uganda: A cross-sectional study
(PLoS ONE, 2023)Background Suboptimal utilization of antiretroviral therapy (ART) services remains a problem among adolescents in low- and middle-income countries, which has a negative impact on their response to treatment and increases ... -
Impact of a Cryptococcal meningitis diagnosis and treatment program at Lira Regional Referral Hospital in rural, Northern Uganda
(PLOS global public health, 2022)Abstract In rural areas of sub-Saharan Africa, infrastructure and resources for treatment of crypto coccal meningitis (CM) are often lacking. We introduced a CM diagnosis and treatment pro gram (CM-DTP) at Lira Regional ... -
Knowledge and compliance with Covid-19 infection prevention and control measures among health workers in regional referral hospitals in northern Uganda: a cross sectional online survey [version 2; peer review: 1 approved, 1 approved with reservations]
(F1000Research, 2021)Background: Infection prevention and control (IPC) has increasingly been underscored as a key tool for limiting the transmission of coronavirus disease 2019 (Covid-19) and safeguarding health workers from infections ... -
Improving the accuracy of heart failure diagnosis in low-resource settings through task sharing and decentralization
(Global Health Action, 2019)Background: Task sharing of TTE may improve capacity for heart failure diagnosis and management in patients in remote, low-resource settings but the impact on diagnostic accuracy and patient outcomes has not been ... -
Uptake and Associated Factors of Male Contraceptive Method Use: A Community-Based Cross-Sectional Study in Northern Uganda
(Open Access Journal of Contraception, 2023)Background: Uganda has one of the highest fertility rates in Sub-Saharan Africa (SSA). Improving contraceptive uptake in all genders, including males, may be critical to meeting family planning goals in such a setting. ... -
Depression, suicidality, substance-use and associated factors among people living with HIV the COVID-19 pandemic in Uganda
(PLOS ONE, 2023)Background Mental disorders are common in people living with HIV (PLHIV) but they are often unrecog nized and untreated. Furthermore, the COVID-19 pandemic has disrupted the already lim ited mental health services in low ... -
Factors associated with uptake of human papilloma virus vaccine among school girls aged 9–14 years in Lira City northern Uganda: a cross-sectional study
(BMC Women's Health, 2023)Abstract Background Cervical cancer is the most common Human Papilloma Virus (HPV)-related disease among women. Since 2008, HPV vaccination has been routinely recommended for pre-adolescent and adolescent girls in Uganda ... -
The Role of Community Saving Initiatives in Poverty Reduction: An Appraisal of Saving Groups in Alebtong District, Mid-North Uganda
(International Journal of Poverty, Investment and Development, 2023)Purpose: This study examined the significance of saving groups on poverty reduction in Alebtong district. Three objectives guided the study, viz. (i) to determine the effect of shares provided by saving groups towards ... -
Maternal mental health screening and management by health workers in southwestern Uganda: a qualitative analysis of knowledge, practices, and challenges
(BMC Pregnancy and Childbirth, 2023)Background Maternal mental health (MMH) problems, such as perinatal depression, maternal anxiety, suicide ideation and puerperal psychosis among others, have a significant impact on maternal morbidity and mortality, as ... -
Nodding syndrome in Uganda is a tauopathy
(Acta neuropathologica, 2018)Nodding syndrome is an epidemic neurologic disorder of unknown cause that affects children in the subsistence-farming communities of East Africa. We report the neuropathologic findings in five fatal cases (13–18 years of ... -
The spectrum of disease and tau pathology of nodding syndrome in Uganda
(Brain, 2021)Nodding syndrome is an enigmatic recurrent epidemic neurologic disease that affects children in East Africa. The illness begins with vertical nodding of the head and can progress to grand mal seizures and death after ... -
A systematic review and meta-analysis of the prevalence of depression among breast cancer patients in Sub-Saharan Africa
(Avicenna Journal of Neuro Psycho Physiology, 2023)Background: Breast cancer is linked to neuropsychiatric conditions, particularly depression, which lowers life expectancy. Studies from Sub-Saharan Africa, however, have revealed conflicting prevalence rates of ... -
Plasma levels of DDE/DDT and liver function in malaria control personnel 6 months after indoor residual spraying with DDT in northern Uganda, 2008
(South African Medical Journal, 2008)Objective. We investigated the relationship between plasma levels of dichlorodiphenyltrichloroethane (DDT) and liver function in malaria control personnel 6 months after one round of DDT indoor residual spraying ... -
Neuroinflammation and Not Tauopathy Is a Predominant Pathological Signature of Nodding Syndrome
(Journal of Neuropathology & Experimental Neurology, 2019)Nodding syndrome (NS) is an epileptic disorder occurring in chil dren in African onchocerciasis endemic regions. Here, we describe the pathological changes in 9 individuals from northern Uganda who died with NS (n ¼ 5) ... -
Neuropathological Changes in Nakalanga Syndrome—A Case Report
(Pathogens, 2021)Nakalanga syndrome is a clinical manifestation of onchocerciasis-associated epilepsy characterized by stunting, delayed or absent secondary sexual development and skeletal deformities, and is often accompanied by epileptic ... -
Chronic stress and its correlates among nurses: A case of Central Uganda
(Avicenna J Neuro Psycho Physiology, 2023)Background: Despite an overwhelming disease burden, nursing shortages are evident in Sub-Saharan Africa, with the potential for significant healthcare crises. Nurses face increased work demands and chronic stress due to a ... -
Health-seeking behaviour regarding schistosomiasis treatment in the absence of a mass drug administration (MDA) program: the case of endemic communities along Lake Albert in Western Uganda
(BMC Public Health, 2023)Introduction Schistosomiasis poses a serious public health problem and a social challenge affecting over 240 million people, the majority of whom live in sub-Saharan Africa. The World Health Organization (WHO) recommends ...