Now showing items 1-2 of 2

    • Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial 

      Maitland, Kathryn; George, Elizabeth C; Evans, Jennifer; Kiguli, Sarah; Olupot-Olupot, Peter; Akech, Samuel O; Opoka, Robert O; Engoru, Charles; Nyeko, Richard; Mtove, George; Reyburn, Hugh; Brent, Bernadette; Nteziyaremye, Julius; Mpoya, Ayub; Prevatt, Natalie; Dambisya, Cornelius M; Semakula, Daniel; Ddungu, Ahmed; Okuuny, Vicent; Wokulira, Ronald; Otii, Benedict; Levin, Michael; Crawley, Jane; Babiker, Abdel G; Gibb, Diana M; FEAST trial group (2013)
      Background: Early rapid fluid resuscitation (boluses) in African children with severe febrile illnesses increases the 48-hour mortality by 3.3% compared with controls (no bolus). We explored the effect of boluses on 48-hour ...
    • High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda 

      Olupot-Olupot, Peter; Engoru, Charles; Uyoga, Sophie; Muhindo, Rita; Macharia, Alex; Kiguli, Sarah; Opoka, Robert O; Akech, Samuel; Ndila, Carolyne; Nyeko, Richard; Mtove, George; Nteziyaremye, Julius; Chebet, Martin; George, Elizabeth C; Babiker, Abdel G; Gibb, Diana M; Williams, Thomas N.; Maitland, Kathryn (Clinical Infectious Diseases, 2017)
      Background. In the Fluid Expansion as a Supportive Treatment (FEAST) trial, an unexpectedly high proportion of participants from eastern Uganda presented with blackwater fever (BWF). Methods. We describe the prevalence ...