Browsing Department of Pharmacology by Author "Kyegombe, David B."
Now showing items 1-5 of 5
-
Anti-Plasmodium falciparum activity of Aloe dawei and Justicia betonica
Bbosa, Godfrey S.; Kyegombe, David B.; Lubega, Aloysius; Musisi, Nathan; Ogwal-Okeng, Jasper; Odyek, Olwa (African Journal of Pharmacy and Pharmacology, 2013)Malaria is a fatal disease caused by different Plasmodium species of parasites and has remained the major killer of humans worldwide especially the children under five years of age and pregnant women. In this study, the ... -
Chronic alcohol use reduces CD4+counts in HIV/AIDS patients on d4T/3TC/NVP treatment regimen using WHO AUDIT tool and alcohol-use biomarkers
Bbosa, Godfrey S.; Kyegombe, David B.; Anokbonggo, William W.; Mugisha, Apollo; Ogwal-Okeng, Jasper (Research & Reviews in BioSciences, 2014)Alcohol is one of the most abused drugs worldwide by people of different socio-economic status, age groups and including the HIV/AIDS patient on treatment. It is reward drug and a CNS depressant especially at high doses. ... -
Chronic ethanol use in alcoholic beverages by HIV-infected patients affects the therapeutic window of stavudine, lamivudine and nevirapine during the 9-month follow-up period: using chronic alcohol-use biomarkers
Bbosa, Godfrey S.; Kyegombe, David B.; Anokbonggo, William W.; Ogwal-Okeng, Jasper; Musoke, David; Odda, John; Lubega, Aloysius; Ntale, Muhammad (Journal of Basic and Clinical Physiology and Pharmacology, 2013)Background: Chronic ethanol use is a global problem including among HIV-infected patients on stavudine/ lamivudine/nevirapine (d4T/3TC/NVP) regimen. The study determined the effect of chronic ethanol use on the therapeutic ... -
Does chronic alcohol use by HIV-infected patients on d4T/3TC/NVP drug regimen effect the HIV viral load and what is the therapeutic window of the drugs, CD4+ count and WBC count in patients with high viral load during the 9 months period of follow up?
Bbosa, Godfrey s.; Anokbonggo, william w; Kyegombe, David B.; Ntale, Muhammad; Mugisha, Apollo; Musoke, David; Ogwal-Okeng, Jasper (International Journal of Basic & Clinical Pharmacology, 2013)The study investigated the effects of chronic alcohol use on HIV viral load in HIV-infected patients on d4T/3TC/NVP drug regimen during 9 months follow up period. It also determined plasma drug concentrations of d4T, 3TC ... -
Review of the Biological and Health Effects of Aflatoxins on Body Organs and Body Systems
Bbosa, Godfrey S.; Kitya, David; Lubega, A.; Ogwal-Okeng, Jasper; Anokbonggo, William W.; Kyegombe, David B. (InTech, 2013)Aflatoxins are a group of naturally occurring carcinogens that are known to contaminate different human and animal food stuffs. Aflatoxins are poisonous by-products from soil-borne fungus Aspergillus, which is responsible ...