Browsing Department of Pharmacology by Title

Now showing items 29-41 of 41

    • Medical Foods and Infant Formulas 

      Mtewa, Andrew G.; Kasali, Mushagalusa F.; Bekele, Tamirat; Obura, Bonniface (Springer, 2020)
      Medical foods are foods that are formulated specifically to help in the management of diseases with particular dietary needs hardly met singly by normal diet. They are taken under medical prescription or supervision. On ...

    • A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. 

      Mukonzo, Jackson K.; Röshammar, Daniel; Waako, Paul J; Andersson, Maria; Fukasawa, Takashi; Milani, Lili; Svensson, Jan Olof; Ogwal-Okeng, Jasper; Gustafsson, Lars L; Aklillu, Eleni (British Journal of Clinical Pharmacology, 2009)
      AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ...

    • Off-label antibiotic use among paediatric in-patients: a mixed-method prospective study at a tertiary hospital in southwestern Uganda 

      Obura, Bonniface; Obua, Celestino (International Journal of Clinical Pharmacy, 2020)
      Background The off-label use of drugs to treat children is a global practice attributed to the traditional exclusion of children from clinical trials mainly due to practical and ethical reasons. Off-label drug use carries ...

    • Patterns and Predictors of Self-Medication in Northern Uganda 

      Ocan, moses.; Bwanga, freddie; Bbosa, Godfrey s; Bagenda, Danstan; Waako, paul.; Ogwal-Okeng, Jasper; Obua, Celestino (PLOS ONE, 2014)
      Self-medication with antimicrobial agents is a common form of self-care among patients globally with the prevalence and nature differing from country to country. Here we assessed the prevalence and predictors of antimicrobial ...

    • Phytochemical Analysis and Screening of Ugandan Medicinal Plants for Antifungal Activity against Candida albicans 

      Kakudidi, Esazah.; Ayorekire, Fredric; Ogwal-Okeng, Jasper; Anywar, Godwin (International Journal of Tropical Disease & Health, 2015)
      Aims: The potential activity against Candida albicans of five commonly used medicinal plant species of Bwindi Impenetrable Forest National Park in southwestern Uganda was investigated. Study Design: The phytochemical ...

    • Phytochemicals and acute toxicity of Moringa oleifera roots in mice 

      Kasolo, J. N.; Bimenya, G. S.; Ojok, L.; Ogwal-Okeng, Jasper (Journal of Pharmacognosy and Phytotherapy, 2011)
      The phytochemicals used by plants to protect themselves against predators in Moringa oleifera roots were qualitatively identified in the aqueous and ethanol extracts. Its acute toxicity in 24 h was evaluated in Swiss albino ...

    • Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities 

      Kasolo, Josephine N; Bimenya, Gabriel S.; Ojok, Lonzy; Ochieng, Joseph; Ogwal-Okeng, Jasper (Journal of Medicinal Plants Research, 2010)
      Moringa oleifera grown and used in many countries around the world is a multi-purpose tree with medicinal, nutritional and socio-economic values. In Senegal and Benin, M. oleifera leaves are dispensed as powder at health ...

    • Prevalence and predictors of prior antibacterial use among patients presenting to hospitals in Northern Uganda 

      Ocan, MOSES; Manabe5, Yukari C.; Baluku, Hannington; Atukwase, Esther; Ogwal-Okeng, Jasper; Obua, celestino (BioMed Central, 2015)
      Background: Human antibacterial exposure occur in different ways including consumption of animal and agricultural products as well as use of prescribed and non-prescribed agents. We estimated the prevalence and explored ...

    • Prevalence of K13-propeller gene polymorphisms among Plasmodium falciparum parasites isolated from adult symptomatic patients in northern Uganda 

      Ocan, Moses; Bwanga, Freddie; Okeng, Alfred; Katabazi, Fred; Kigozi, Edgar; Kyobe, Samuel; Ogwal-Okeng, Jasper; Obua, Celestino (BioMed Central, 2016)
      Background: In the absence of an effective vaccine, malaria treatment and eradication is still a challenge in most endemic areas globally. This is especially the case with the current reported emergence of resistance to ...

    • Review of the Biological and Health Effects of Aflatoxins on Body Organs and Body Systems 

      Bbosa, Godfrey S.; Kitya, David; Lubega, A.; Ogwal-Okeng, Jasper; Anokbonggo, William W.; Kyegombe, David B. (InTech, 2013)
      Aflatoxins are a group of naturally occurring carcinogens that are known to contaminate different human and animal food stuffs. Aflatoxins are poisonous by-products from soil-borne fungus Aspergillus, which is responsible ...

    • Traditional herbal remedies for managing COVID-19 major symptoms: A case study of Kole district, Northern Uganda 

      Nakaziba, Rebecca; Anyolitho, Maxson Kenneth; Kabunga, Amir (TMR Pharmacology Research, 2021)
      Background: Today, the world is battling COVID-19 which has claimed millions of lives within a short period. As biotechnological research is in progress, it’s expedient to explore alternative sources of medication. Exploring ...

    • Traditional Medicinal Vegetables in Northern Uganda: An Ethnobotanical Survey 

      Nakaziba, Rebecca; Anyolitho, Maxson Kenneth; Amanya, Sharon Bright; Sesaazi, Crispin Duncan; Byarugaba, Frederick; Ogwal-Okeng, Jasper; Alele, Paul E. (International Journal of Food Science, 2021)
      Background. A wide range of indigenous vegetables grow in Uganda especially during rainy seasons but scarcely during droughts, except those that are commercially grown. Although a number of these vegetables have medicinal ...

    • Use of a pilot drug information centre 

      Tumwikirize, A W; Ogwal-Okeng, Jasper; Vernby, A; Anokbonggo, W W; Gustafsson, L L; Lundborg, C S (African Health Sciences, 2011)
      Introduction: Provision of access to drug information by prescribers and other health care professionals is important in pharmacotherapy. At the time of this study there was very scanty literature in this area from ...