Faculty of Medicine: Recent submissions
Now showing items 81-100 of 204
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Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial
(2013)Background: Early rapid fluid resuscitation (boluses) in African children with severe febrile illnesses increases the 48-hour mortality by 3.3% compared with controls (no bolus). We explored the effect of boluses on 48-hour ... -
HIV-free survival among breastfed infants born to HIV-positive women in northern Uganda: a facility-based retrospective study
(Pan African Medical Journal, 2020)Introduction: the HIV-free survival rate is the gold-standard measure of the effectiveness of interventions towards prevention of mother-to-child transmission of HIV in any setting. However, data on HIV-free survival among ... -
Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa
(BMC Medicine, 2018)Background: Hyperlactataemia (HL) is a biomarker of disease severity that predicts mortality in patients with sepsis and malaria. Lactate clearance (LC) during resuscitation has been shown to be a prognostic factor of ... -
Unsatisfactory COVID-19-Related Knowledge, Attitudes and Practices among Undergraduate University Students in Uganda: An Online Cross-Sectional Survey
(Open Journal of Preventive Medicine, 2021)Background: This study examined the COVID-19-related knowledge, attitude and practices among undergraduate students in Uganda. Methods: An online cross-sectional survey was conducted from 12th-19th June 2020 among undergraduate ... -
Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness
(BMC Medicine, 2015)Background: Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group. Methods: ... -
High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda
(Clinical Infectious Diseases, 2017)Background. In the Fluid Expansion as a Supportive Treatment (FEAST) trial, an unexpectedly high proportion of participants from eastern Uganda presented with blackwater fever (BWF). Methods. We describe the prevalence ... -
WHO guidelines on fluid resuscitation in children : Authors’ reply to Southall
(BMJ Publishing Group Ltd, 2014)Southall made several points about our recent article.1 2 He suggests that “lethal hyperchloraemia” secondary to use of normal saline in FEAST (for boluses or maintenance) resulted in excess mortality. However, he did ... -
Prevalence and factors associated with use of herbal medicines during pregnancy among women attending postnatal clinics in Gulu district, Northern Uganda
(BMC Pregnancy and Childbirth, 2016)Background: According to World Health Organization (WHO) estimates, 80 % of the population living in rural areas in developing countries depends on traditional medicine for their health needs, including use during pregnancy. ... -
Impaired renal function and associated risk factors in newly diagnosed HIV-infected adults in Gulu Hospital, Northern Uganda
(BMC nephrology, 2015)Background: Screening for renal diseases should be performed at the time of diagnosis of human immunodeficiency virus (HIV) infection. Despite the high prevalence of HIV/AIDS in Northern Uganda, little is known about the ... -
Are Women In Low Income Setting Gaining Adequate Gestational Weight? A Prospective Cross Sectional Study In Urban Uganda
(School of Biological Sciences, 2016)Introduction: Pre-pregnancy weight and weight gained during pregnancy significantly influence maternal and infant health. Little information is available regarding prevalence of optimal GWG in relation to pre-pregnancy body ... -
Health seeking behaviour of small income market vendors: Diabetes primary care in Gulu Municipality, northern Uganda
(South Sudan Medical Journal, 2020)Introduction: Uganda faces a serious threat of non-communicable diseases including type 2 diabetes; sedentary lifestyles predispose people to these diseases. Objective: To understand the diabetes health seeking behaviour ... -
Antibiograms from community-acquired uropathogens in Gulu, northern Uganda - a cross-sectional study
(BMC infectious diseases, 2013)Background: Urinary tract infections (UTI) are common in clinical practice and empirical treatment is largely employed due to predictability of pathogens. However, variations in antibiotic sensitivity patterns do occur, ... -
Prevalence of anaemia and associated risk factors among pregnant women attending antenatal care in Gulu and Hoima Regional Hospitals in Uganda: A cross sectional study
(BMC pregnancy and childbirth, 2016)Background: Anaemia is a public health problem affecting over 1.62 billion people globally. It affects all age groups of people and is particularly more prevalent in pregnant women. Africa carries a high burden of ... -
WHO guidelines on fluid resuscitation in children: missing the FEAST data
(Bmj, 2014)The World Health Organization recommendations on management of common childhood illnesses affect the lives of millions of children admitted to hospital worldwide. Its latest guidelines,1 released in May 2013, continue ... -
Treatment outcome among children underfive years hospitalized with severe acute malnutrition in St. Mary’s hospital Lacor, Northern Uganda
(BMC Nutrition, 2016)Background: Severe malnutrition contributes to more than 60 % of deaths in children in developing countries. The minimum international standard set for management of severe acute malnutrition is a cure rate of at least ... -
Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score
(BMC Medicine, 2015)Background: Mortality in paediatric emergency care units in Africa often occurs within the first 24 h of admission and remains high. Alongside effective triage systems, a practical clinical bedside risk score to identify ... -
Mortality risk over time after early fluid resuscitation in African children
(Clinical care, 2019)Background: African children hospitalised with severe febrile illness have a high risk of mortality. The Fluid Expansion As Supportive Therapy (FEAST) trial (ISCRTN 69856593) demonstrated increased mortality risk ... -
Mortality after Fluid Bolus in African Children with Severe Infection
(New England Journal of Medicine, 2011)Background The role of fluid resuscitation in the treatment of children with shock and lifethreatening infections who live in resource-limited settings is not established. Methods We randomly assigned children with ... -
Lactose intolerance among severely malnourished children with diarrhoea admitted to the nutrition unit, Mulago hospital, Uganda
(BMC Pediatrics, 2010)Background: Lactose intolerance is a common complication of diarrhoea in infants with malnutrition and a cause of treatment failure. A combination of nutritional injury and infectious insults in severe protein energy ... -
Traditional Medicinal Vegetables in Northern Uganda: An Ethnobotanical Survey
(International Journal of Food Science, 2021)Background. A wide range of indigenous vegetables grow in Uganda especially during rainy seasons but scarcely during droughts, except those that are commercially grown. Although a number of these vegetables have medicinal ...
