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Prevalence of K13-propeller gene polymorphisms among Plasmodium falciparum parasites isolated from adult symptomatic patients in northern Uganda
(BioMed Central, 2016)
Background: In the absence of an effective vaccine, malaria treatment and eradication is still a challenge in most
endemic areas globally. This is especially the case with the current reported emergence of resistance to ...
CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population
(Future Medicine Ltd: Pharmacogenomics, 2016)
To assess genotype effect on efavirenz (EFV) pharmacokinetics, treatment
outcomes and provide genotype-based EFV doses recommendations during for
tuberculosis (TB)-HIV-1 cotreatment. Materials & methods: EFV concentrations
from ...
Incomplete reversal of genotypic resistance of Plasmodium falciparum to chloroquine after a decade of change in malaria treatment policy in Uganda
(Reports in Parasitology, 2016)
Background: The potential re-emergence of Plasmodium falciparum parasites sensitive to chloroquine provides an opportunity for the reintroduction of the drug in patient care. With the recent discovery and spread of artemisinin ...