Browsing Faculty of Medicine by Title

Now showing items 114-133 of 191

    • Major limb loss (MLL): An overview of etiology, outcomes, experiences and challenges faced by amputees and service providers in the post-conflict period in Northern Uganda 

      Okello, Tom Richard; Magada, Samuel M; Atim, Pamela; Ezati, Daniel; Campion, Alice; Moro, Emmanuel B; Huck, Jonathon; Byrne, Ged; Redmond, Anthony; Nirmalan, Mahesh (Journal of Global Health Reports, 2019)
      Background Trauma is a leading cause for major limb loss (MLL) during war. As societies transition into peace other factors become important. The voluntary sector plays a diminishing role in service delivery as countries ...

    • Major Limb Loss and Prosthesis Use in the Post Conflict era in Acholi Sub-Region, Northern Uganda 

      Okello, Tom Richard; Magada, Samuel Moses; Atim, Pamela; Campion, Alice; Moro, Emmanuel Ben; Jonathan, Hucks; Mahesan, Nirmalan (International Journal of Science Academic Research, 2022)
      Introduction: This study assessed amputees’ residual limb stump in the post war era of Acholi sub-region for suitability of prosthetic fit use and associated challenges with their current prosthesis and psycho-socio ...

    • Medical Foods and Infant Formulas 

      Mtewa, Andrew G.; Kasali, Mushagalusa F.; Bekele, Tamirat; Obura, Bonniface (Springer, 2020)
      Medical foods are foods that are formulated specifically to help in the management of diseases with particular dietary needs hardly met singly by normal diet. They are taken under medical prescription or supervision. On ...

    • Mental Health during COVID-19 Pandemic: Does Social Support Count? A Cross-Sectional Survey among Lira University Students, Northern Uganda 

      Anyolitho, Maxson Kenneth; Kabunga, Amir; Anyayo, Lucas Goodgame; Nakaziba, Rebecca (PQ Neurology and Psychology, 2021)
      COVID-19 pandemic that began in Wuhan, China towards the end of 2019 is the world’s catastrophe of the 21st-century. As a result, the pandemic has disrupted all sectors of the world’s economies including the education ...

    • Mortality after Fluid Bolus in African Children with Severe Infection 

      Maitland, Kathryn; Kiguli, Sarah; Opoka, Robert O.; Engoru, Charles; Olupot-Olupot, Peter; Akech, Samuel O.; Nyeko, Richard; Mtove, George; Reyburn, Hugh; Lang, Trudie; Brent, Bernadette; Evans, Jennifer A.; Tibenderana, James K.; Crawley, Jane; Russell, Elizabeth C.; Levin, Michael; Babiker, Abdel G.; Gibb, Diana M. (New England Journal of Medicine, 2011)
      Background The role of fluid resuscitation in the treatment of children with shock and lifethreatening infections who live in resource-limited settings is not established. Methods We randomly assigned children with ...

    • Mortality risk over time after early fluid resuscitation in African children 

      George, Elizabeth C.; Kiguli, Sarah; Olupot Olupot, Peter; Opoka, Robert O.; Engoru, Charles; Akech, Samuel O.; Nyeko, Richard; Mtove, George; Mpoya, Ayub; Thomason, Margaret J.; Crawley, Jane; Evans, Jennifer A.; Gibb, Diana M.; Babiker, Abdel G.; Maitland, Kathryn; Walker, A. Sarah (Clinical care, 2019)
      Background: African children hospitalised with severe febrile illness have a high risk of mortality. The Fluid Expansion As Supportive Therapy (FEAST) trial (ISCRTN 69856593) demonstrated increased mortality risk ...

    • Mothers’ perceptions of the practice of kangaroo mother care for preterm neonates in sub-Saharan Africa: a qualitative systematic review protocol 

      Bayo, Pontius; Alobo, Gasthony; Feyissa, Garumma Tolu; Belaid, Loubna (JBI Database of Systematic Reviews and Implementation Reports, 2019)
      Objective: The objective of this review is to explore the experiences of mothers with the practice of kangaroo mother care (KMC) for preterm neonates at home in sub-Saharan Africa. Introduction: About 7000 newborn babies ...

    • Neuroinflammation and Not Tauopathy Is a Predominant Pathological Signature of Nodding Syndrome 

      Hotterbeekx, An; Lammens, Martin; Idro, Richard; Akun, Pamela R.; Lukande, Robert; Akena, Geoffrey; Nath, Avindra; Taylor, Jonee; Olwa, Francis; Kumar-Singh, Samir; Colebunders, Robert (Journal of Neuropathology & Experimental Neurology, 2019)
      Nodding syndrome (NS) is an epileptic disorder occurring in chil dren in African onchocerciasis endemic regions. Here, we describe the pathological changes in 9 individuals from northern Uganda who died with NS (n ¼ 5) ...

    • Neuropathological Changes in Nakalanga Syndrome—A Case Report 

      Hotterbeekx, An; Lammens, Martin; Onzivua, Sylvester; Lukande, Robert; Olwa, Francis; Kumar-Singh, Samir; Van Hees, Stijn; Idro, Richard; Colebunders, Robert (Pathogens, 2021)
      Nakalanga syndrome is a clinical manifestation of onchocerciasis-associated epilepsy characterized by stunting, delayed or absent secondary sexual development and skeletal deformities, and is often accompanied by epileptic ...

    • Nodding syndrome in Uganda is a tauopathy 

      Pollanen, Michael S.; Onzivua, Sylvester; Robertson, Janice; McKeever, Paul M.; Olwa, Francis; Kitara, David L.; Fong, Amanda (Acta neuropathologica, 2018)
      Nodding syndrome is an epidemic neurologic disorder of unknown cause that affects children in the subsistence-farming communities of East Africa. We report the neuropathologic findings in five fatal cases (13–18 years of ...

    • A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. 

      Mukonzo, Jackson K.; Röshammar, Daniel; Waako, Paul J; Andersson, Maria; Fukasawa, Takashi; Milani, Lili; Svensson, Jan Olof; Ogwal-Okeng, Jasper; Gustafsson, Lars L; Aklillu, Eleni (British Journal of Clinical Pharmacology, 2009)
      AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ...

    • Obstetric Referrals to a Tertiary Hospital in Northern Uganda - A One Year Experience 

      Nionzima, Elizabeth; Otim, Tom Charles (Jemds.com, 2020)
      BACKGROUND Delay in referral adversely affects maternal and neonatal outcome. We wanted to review the obstetric referrals, source of referrals, appropriateness of referrals and document the maternal and perinatal outcomes ...

    • Off-label antibiotic use among paediatric in-patients: a mixed-method prospective study at a tertiary hospital in southwestern Uganda 

      Obura, Bonniface; Obua, Celestino (International Journal of Clinical Pharmacy, 2020)
      Background The off-label use of drugs to treat children is a global practice attributed to the traditional exclusion of children from clinical trials mainly due to practical and ethical reasons. Off-label drug use carries ...

    • Oral–visceral iatrogenic Kaposi sarcoma following treatment for acute lymphoblastic leukemia: a case report and review of the literature 

      Nyeko, Richard; Geriga, Fadhil; Angom, Racheal; Kambugu, Joyce Balagadde (Journal of Medical Case Reports, 2022)
      Background: There have hardly been any reported cases of children presenting with Kaposi sarcoma as a second malignancy following treatment for acute lymphoblastic leukemia outside a transplant setting. Case presentation: ...

    • Patterns and Predictors of Self-Medication in Northern Uganda 

      Ocan, moses.; Bwanga, freddie; Bbosa, Godfrey s; Bagenda, Danstan; Waako, paul.; Ogwal-Okeng, Jasper; Obua, Celestino (PLOS ONE, 2014)
      Self-medication with antimicrobial agents is a common form of self-care among patients globally with the prevalence and nature differing from country to country. Here we assessed the prevalence and predictors of antimicrobial ...

    • Personality and Mental Health among Lira University Students during the COVID-19 Pandemic 

      Kabunga, Amir; Anyolitho, Maxson Kenneth; Anyayo, Lucas Goodgame (International Journal of Academic Research in Psychology, 2020)
      Abstract COVID-19 pandemic is one of the 21st -century major health crises affecting the world. Due to the pandemic, education activities were disrupted and examinations were postponed. This could have far-reaching effects ...

    • Phenomenology of Induced Abortion in Northern Uganda Among HIV-Positive Women Following an Unintended Pregnancy 

      Kabunga, Amir; Acanga, Alfred; Akello, Judith Abal; Nabasirye, Caroline Kambugu; Namata, Halimah; Mwesigwa, David; Auma, Anna Grace; Kigongo, Eustes; Udho, Samson (Open Access Journal of Contraception, 2023)
      Background: More than half of pregnancies in Uganda are unintended, and nearly a third of these end in abortion. However, little research has focused on women living with HIV’s subjective experiences following induced ...

    • Phytochemical Analysis and Screening of Ugandan Medicinal Plants for Antifungal Activity against Candida albicans 

      Kakudidi, Esazah.; Ayorekire, Fredric; Ogwal-Okeng, Jasper; Anywar, Godwin (International Journal of Tropical Disease & Health, 2015)
      Aims: The potential activity against Candida albicans of five commonly used medicinal plant species of Bwindi Impenetrable Forest National Park in southwestern Uganda was investigated. Study Design: The phytochemical ...

    • Phytochemicals and acute toxicity of Moringa oleifera roots in mice 

      Kasolo, J. N.; Bimenya, G. S.; Ojok, L.; Ogwal-Okeng, Jasper (Journal of Pharmacognosy and Phytotherapy, 2011)
      The phytochemicals used by plants to protect themselves against predators in Moringa oleifera roots were qualitatively identified in the aqueous and ethanol extracts. Its acute toxicity in 24 h was evaluated in Swiss albino ...

    • Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities 

      Kasolo, Josephine N; Bimenya, Gabriel S.; Ojok, Lonzy; Ochieng, Joseph; Ogwal-Okeng, Jasper (Journal of Medicinal Plants Research, 2010)
      Moringa oleifera grown and used in many countries around the world is a multi-purpose tree with medicinal, nutritional and socio-economic values. In Senegal and Benin, M. oleifera leaves are dispensed as powder at health ...