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Mortality after Fluid Bolus in African Children with Severe Infection
(New England Journal of Medicine, 2011)
Background
The role of fluid resuscitation in the treatment of children with shock and lifethreatening
infections who live in resource-limited settings is not established.
Methods
We randomly assigned children with ...
Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial
(2013)
Background: Early rapid fluid resuscitation (boluses) in African children with severe febrile illnesses increases the
48-hour mortality by 3.3% compared with controls (no bolus). We explored the effect of boluses on 48-hour ...