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Antimalarial Activity of Aspilia pruliseta, a Medicinal Plant from Uganda
(Planta Medica : Journal of Medicinal Plant and Natural Product Research, 2010)
Aspilia prulisetaSchweinf. (Asteraceae) is a medicinal plant in-digenous to Uganda and the neighboring countries of East Africa.It has been used extensively by the rural population for the treat-ment of fevers and malaria. ...
Incomplete reversal of genotypic resistance of Plasmodium falciparum to chloroquine after a decade of change in malaria treatment policy in Uganda
(Reports in Parasitology, 2016)
Background: The potential re-emergence of Plasmodium falciparum parasites sensitive to chloroquine provides an opportunity for the reintroduction of the drug in patient care. With the recent discovery and spread of artemisinin ...
Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa
(BMC Medicine, 2018)
Background: Hyperlactataemia (HL) is a biomarker of disease severity that predicts mortality in patients with sepsis
and malaria. Lactate clearance (LC) during resuscitation has been shown to be a prognostic factor of ...
Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness
(BMC Medicine, 2015)
Background: Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in
sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group.
Methods: ...
High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda
(Clinical Infectious Diseases, 2017)
Background. In the Fluid Expansion as a Supportive Treatment (FEAST) trial, an unexpectedly high proportion of participants
from eastern Uganda presented with blackwater fever (BWF).
Methods. We describe the prevalence ...