Pecorella, IreneNunzia, MannaValeria, CalbiOmona, VeniceOkello, Tom Richard2021-05-122021-05-122021Pecorella, I., Manna, N., Calbi, V., Omona, V., & Okello, T. R. (2021). Bilateral proptosis as an early manifestation of juvenile myelomonocitic leukemia in an African child. Indian Journal of Pathology and Oncology, 8(1), 152–154. https://doi.org/10.18231/j.ijpo.2021.028https://www.ipinnovative.com/open-access-journalshttps://hdl.handle.net/123456789/245We report bilateral proptosis as the unusual initial presentation of juvenile myelomonocytic leukemia in a Ugandan child. Juvenile myelomonocytic leukemia was diagnosed with complete blood count and bone marrow aspiration biopsy. This is the first description of orbital involvement occurring in the setting of juvenile myelomonocytic leukemia, despite leukemic orbital infiltration is relatively common in the middle East, Asia, and Africa. In general, simultaneous neoplastic involvement of both orbits at presentation is also a rare finding, bur appears to be highly likely in leukemic children. © This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.enJuvenile myelomonocytic leukemiaOrbitBilateral proptosisAfricaArticle